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Absidia A zygomycete fungus. Reported to be allergenic. May cause mucorosis in immune compromised individuals. The sites of infection are the lung, nasal sinus, brain, eye and skin. Infection may have multiple sites.
Acremonium(Cephalosporium) Reported to be allergenic. Can produce a trichothecene toxin that is toxic if ingested. It was the primary fungus identified in at least two houses where the occupant complaints were nausea, vomiting and diarrhea. Asexual state ofEmericellopsissp.,Chaetomiumsp., andNectripsissp. It can produce mycetomas, infections of the cornea and nails
Alternaria
Aw - 0.89. Conidia dimensions: 18-83 x 7-18 microns. This is one of the main fungal causes of allergy, being a common type I (ex.: hay fever, asthma) & type III (ex.: hypersensitivity pneumonitis) allergen. The large spore size suggests that this fungus will settle in the nose, mouth, and upper respiratory tract, causing nasal septum infections.Alternariais a common cause of extrinsic asthma, with acute symptoms including edema and bronchiospasms; chronic cases may develop pulmonary emphysema. “Baker’s asthma” is commonly associated with inhalation ofAlternariaconidia present in flour. Other diseases caused by this mold include: “farmer’s lung”, “woodworker's lung”, “apple store hypersensitivity”, mycotic keratitis (fungal infection of the cornea), nasal lesions, subcutaneous lesions, skin infections, nail infections, and osteomyelitis (inflammation of the bone). [It should be noted that most of the reported infections affected persons with underlying disease or those taking immunosuppressive drugs.]
Toxic metabolites (that may cause disease in humans) produced by these microbes include AME (alternariol monomethylether), tenuazonic acid, and altertoxins (which are mutagenic). Several species are pathogenic to plants, and some are processed for use in the biocontrol of weeds and other plants. A. alternataproduces alternariol, an antifungal metabolite.
Alternariais commonly found indoors in dust, carpeting, textiles, on foodstuffs, and horizontal surfaces (such as window frames). It has also been isolated from substrates such as sewage, leather, stone monuments, optical instruments, cosmetics, computer disks, and even jet fuel. Outdoors, it may be found on dead organic debris, seeds, plants (and can contribute to the spoilage of agricultural products), in soil, and air--one of the reasons that it is a widespread genus. Alternariaconidia are easily carried by the wind, with peak air concentrations occurring in the summer and early fall. Colonies grow fast, are suede-like to floccose, and black to olivaceous-black or grayish in color.
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Amerospore
A spherical or oval single-celled fungal spore that is practically unidentifiable by itself. Genera with this type of spore include, but are not limited to,Aspergillus,Penicillium,Trichoderma. For example,Penicilliumis easily identifiable when sampling using culturing techniques. However, when sampling with non-culturing techniques, such as spore traps or tape-lifts, the free spores with no remnants of the fungal structure are indistinguishable fromAspergillusand various other genera that also produce small round and oval spores with little or no pigmentation. Due to this fact, Penicillium will often be categorized on laboratory reports in an "amerospore" and/or "Aspergillus/Penicillium" group.
Arthrinium
Widespread saprophyte found on decomposing plant material, particularly grasses, and on soil. It is a white, fuzzy mold. It should be considered to be an allergen. This fungus has also been documented in various subcutaneous infections. No diseases related to toxic effects have been recorded to date.
Ascospore
A spore borne in a special cell called an ascus. Spores of this type are reported to be allergenic. All ascomycetes, members of a group of fungi called Ascomycotina, have this type of spore. The minute black dots on rotting wood and leaves or the little cups on lichens are examples of ascomycetes; another is the "truffle" mushroom.
Aspergillus caesiellus
This species is only occasionally pathogenic.
Aspergillus candidus
Aw 0.75. Conidia dimensions: 2.5-4 microns. Found in warm soils, grain and in the secondary decay of vegetation. Associated with respiratory complaints in a recent house investigation. Can produce the toxin petulin that may be associated with disease in humans and other animals.
Aspergillus carneus This species is only occasionally pathogenic.
Aspergillus clavatus Conidia dimensions: 3-4.5 x 2.5-4.5 microns. Found in soils and animal manure. Can produce the toxin petulin that may be associated with disease in humans and other animals. This species is only occasionally pathogenic.
Aspergillus deflectus This species is only occasionally pathogenic.
Aspergillus flavus Aw 0.78. Conidia dimensions: 3-6 microns or 3-5 microns. It grows on moldy corn and peanuts. It can be found in warm soil, foods and dairy products. Some strains are capable of producing a group of mycotoxins- in the aflatoxin group.Aflatoxins are known animal carcinogens. There is limited evidence to suggest that this toxin is a human carcinogen. The toxin is poisonous to humans by ingestion. It may also result in occupational disease via inhalation. Experiments have indicated that it is teratogenic and mutagenic. It is toxic to the liver.It is reported to be allergenic. Its presence is associated with reports of asthma. It can be found in water-damaged carpets. The production of the fungal toxin is dependent on the growth conditions and on the substrate used as a food source. This fungus is associated with aspergillosis of the lungs and/or disseminated aspergillosis. This fungus is occasionally identified as the cause of corneal,otomycotic and nasoorbital infections.
Aspergillus
fumigatus Aw 0.82; Optimum> 0.97. Conidia dimensions: 2-3.5 microns. Considered a human pathogen, this organism causes both allergic aspergillosis and invasive aspergillosis (invasive aspergillosis usually affects individuals who are immune compromised). It is commonly found outdoors on cereal grains, in cool to warm soils, and in compost piles (even with temperatures exceeding 40 degrees C).
Aspergillus glaucus Conidia dimensions: 5-6.5 microns.Common outdoor fungus in the winter. It is reported to be allergenic. This species is only occasionally pathogenic. It can grow on leather. This fungus can grow at low moisture levels on grains, sugary food products, meat and wool. The ascomycetous state isEurotiumsp.
Aspergillus nidulans Aw 0.78. Conidia dimensions: 2-4 microns. Found in mild to warm soils and on slowly decaying plants. Can produce the mycotoxin sterigmatocystin. This toxin has been shown to produce liver and kidney damage in lab animals. This fungus is associated with aspergillosis of the lungs and/or disseminated aspergillosis. This species is only occasionally pathogenic.
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Aspergillus niger
Aw 0.77; Optimum> 0.97. Conidia dimensions: 3.5 - 5 microns or 4 to 5 microns. Less common cause of aspergillosis. It has a musty odor. It is commonly found in the environment on textiles, in soils, grains, fruits and vegetables. It has been reported to cause skin and pulmonary infections. It is a common cause of fungal related ear infections, including otomycosis.
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Aspergillus ochraceus Aw 0.77. Conidia dimensions: 2.5 - 3 microns. Found in grains, soil and salted food products. It is not usually associated with decaying vegetation. Can produce a kidney toxin ochratoxin A that may produce ochratoxicosis in humans. This is also known as Balkan nephropathy. The toxin is produced at optimum growth conditions at 25 degrees C and high moisture conditions. The ochratoxin may also be produced by otherAspergillussp.andPenicilliumsp.Other toxins that can be produced by this fungus include penicillic acid, xanthomegnin and viomellein. These are all reported to be kidney and liver toxins.
Aspergillus oryzae This species is only occasionally pathogenic.
Aspergillus parasiticus Some strains are capable of producing a group of mycotoxins- in the aflatoxin group. Aflatoxins are known animal carcinogens. There is limited evidence to suggest that this toxin is a human carcinogen. The toxin is a poisonous to humans by ingestion. Experiments have indicated that it is teratogenic and mutagenic. It is toxic to the liver. The production of the fungal toxin is dependent on the growth conditions and on the substrate used as a food source.
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Aspergillus/Penicillium-Like This category is included on laboratory analysis reports for air samples containing certain free spores without other identifying structures. The free spores ofAspergillusandPenicillium(and other genera with small, round or ovoid, and colorless spores) are essentially indistinguishable, using standard microscopic examination methods.
If required, cultured specimens can provide additional characteristics that will enable technicians to determine what genus is represented. If sporulating structures are present,Aspergillusis readily identifiable on tape samples. [Discovery of theAspergillusspecies requires the culture of the fungus under different conditions of media, humidity, and temperature. IdentifyingPenicilliumspecies is difficult, but, in some cases, possible.]
These two allergenic molds are among those most often found in contaminated buildings.Aspergillusis represented by numerous species, many of which produce toxic substances. It may be associated with symptoms such as sinusitis, allergic bronchiopulmonary aspergillosis, and other allergic symptoms. As if not to be outdone, Penicilliumtoo is found in increased numbers in interiors. Some of its many species produce toxic substances that can cause allergic reactions, mucous membrane irritation, headaches, vomiting, and diarrhea.
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Aspergillus penicilloides Conidia dimensions: 3-3.5 x 4-5 microns. Can grow in areas with low water activity. It is found in house dust and food.
Aspergillus restrictus This species is only occasionally pathogenic.
Aspergillus Aw 0.75 - 0.82. Reported to be allergenic.Members of this genus are reported to cause ear infections. Many species produce mycotoxins that may be associated with disease in humans and other animals. Toxin production is dependent on the species or a strain within a species and on the food source for the fungus. Some of these toxins have been found to be carcinogenic in animal species. Several toxins are considered potential human carcinogens. Common cause of extrinsic asthma (immediate-type hypersensitivity: type I). Acute symptoms include edema and bronchiospasms; chronic cases may develop pulmonary emphysema; may also be associated with sinusitis, allergic bronchiopulmonary aspergillosis, and other allergic symptoms.
Aspergillus sydowi This species is only occasionally pathogenic.
Aspergillus terreus Aw 0.78. Conidia dimensions: 1.8-2.4 microns or 2 - 2.5 microns. Aleurospores 6 - 7 microns in diameter are also produced. Found in warmer soil and in grains, straw, cotton and decomposing vegetation. Can produce the toxin patulin and citrinin that may be associated with disease in humans and other animals. This fungus is associated with aspergillosis of the lungs and or disseminated aspergillosis. Found as an isolate from otomycosis - ear infection, and onychomycosis - infection of finger or toenails.
Aspergillus ustus This species is only occasionally pathogenic.
Aspergillus versicolor Aw 0.78. Conidia dimensions: 2-3.5 microns. Mostly in temperate zones, it is commonly found in air, house dust, foods (including dairy products), soil, hay, and cotton. It sometimes produces the mycotoxin "sterigmatocystin", which can cause diarrhea and upset stomach, and is a possible carcinogen, affecting the liver and kidneys. Various other toxins are associated withA. versicolor, such as aspercolorin, averufin, cyclopiazonic acid, and versicolorin. Additionally, the volatile organic compound (VOC) "geosmin" is generated by the action of this mold. Often an irritant to mucus membranes of humans and pets, geosmin has a musty, earthy odor.
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Aureobasidium
Found in soil, forest soils, fresh water, aerial portion of plants, fruit, marine estuary sediments, wood. Allergen, Type I allergies (hay fever, asthma). Type III hypersensitivity pneumonitis: "humidifier fever", "sauna taker's lung". Growth indoors is widespread where moisture accumulates- especially bathrooms and kitchens- on shower curtains, tile grout, windowsills, textiles, liquid waste materials. Potential toxic production is not known. Rare reports of: isolates from skin lesions, keratitis, spleen abscess in a lymphoma patient, blood isolate from a leukemic patient.
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Basidiomycetes Taxonomic designation for fungi of the subdivision "Basidiomycotina", which includes mushrooms and puffballs. They produce spores that are formed on the outside of a special cell, called the "basidium".
basidiospore An exogenous sexual spore (meiospore) borne on a basidium. Or, a spore from a basidiomycete (a member of Basidiomycetes). Many varieties are reported to be allergenic.
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Bipolaris
A fungus with large spores that could be expected to be deposited in the upper respiratory tract. This fungus can produce the mycotoxin - sterigmatocystin, which has been shown to produce liver and kidney damage when ingested by laboratory animals.
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Blastomyces Human pathogen. The fungus is commonly found in soil. It is a dimorphic fungus that has filamentous fungus when grown at 25 degrees C. and a yeast form at 37 degrees C.
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Botrytis
Aw 0.93.Conidia dimensions: 7-14 x 5-9 microns. It is parasitic on plants and soft fruits. Found in soil and on house plants and vegetables, it is also known as "gray mold". It causes leaf rot on grapes, strawberries, lettuce, etc. It is a well-known allergen, producing asthma type symptoms in greenhouse workers and the symptoms of "wine grower's lung".
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Candida Part of the normal flora of mouth and other mucous membranes in the body. Thrush and other diseases caused byCandida albicansusually occur after prolonged treatment with antibiotics or steroids. The environment is not a likely source of exposure for this fungus. Cells from the organism are usually not airborne. Reported to be allergenic.
Cephalosporium SeeAcremonium
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Chaetomium
Large ascomycetous fungus producing perithecia. It is found on a variety of substrates containing cellulose, including paper and plant compost. It has been found on paper in sheetrock. It can produce anAcremonium-like state on fungal media. Varieties are considered allergenic and have been associated with peritonitis, cutaneous lesions, and system mycosis.
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Cladosporium fulvum(Fulvia fulva) Conidia dimensions: 12-47 x 4-10 microns. It is found on the leaves of tomatoes.
Cladosporium herbarum Aw 0.88. Conidia dimensions: 5-23 x 3-8 microns. It is found on dead plants, woody plants, food, straw, soil, paint and textiles.
Cladosporium macrocarpum Conidia dimensions: 9-29 x 5-13 microns. It is found on dead plants, woody plants, food, straw, soil, paint, and textiles.
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Cladosporium(Hormodendrum)
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Cladosporium cladosporoides |
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Aw 0.88; Aw 0.84. Most commonly identified outdoor fungus. The outdoor numbers are reduced in the winter. The numbers are often high in the summer. Often found indoors in numbers less than outdoor numbers. It is a common allergen. IndoorCladosporiumsp. may be different than the species identified outdoors. It is commonly found on the surface of fiberglass duct liners in the interior of supply ducts. A wide variety of plants are food sources for this fungus. It is found on dead plants, woody plants, food, straw, soil, paint, and textiles. Produces greater than 10 antigens. Antigens in commercial extracts are of variable quality and may degrade within weeks of preparation. Common cause of extrinsic asthma (immediate-type hypersensitivity: type I). Acute symptoms include skin lesions, eye ulceration, mycosis (including onychomycosis, an infection of the nails of the feet or hands) edema and bronchiospasms; chronic cases may develop pulmonary emphysema.
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Cladosporium sphaerospermum Conidia dimensions: 3-4.5 microns. It is found as a secondary invader of plants, food, soil, paint and textiles.
conidium A thin-walled, asexual spore borne exogenously on an often specialized hypha (conidiophore) and is deciduous at maturity. (plural form: conidia.)
conidia, unidentified These are mold spores that do not show morphological characteristics that allow identification. Because there are tens of thousands of types of fungi, many fall into the "other" or "unknown" category. If they are present in significant numbers, additional measures can be taken to identify them. When spore counts are listed in the category: "Unidentified Conidia" their numbers are considered "normal".
Conidobolus Can cause a chronic inflammatory disease of the nasal mucosa (entomophthoromycosis).
Cryptococcus neoformans A basidiomycetous encapsulated fungal organism found worldwide, mainly around pigeon roosts and soil contaminated with decaying pigeon or chicken droppings. It is generally accepted that the organism enters the host by the respiratory route in the form of a dehydrated haploid yeast or as basidiospores. Hematogenously spreading to extrapulmonary tissues, its predilection for the brain means infected persons usually contract meningoencephalitis, which can be fatal.
Cryptostroma corticale Conidia dimensions: 4-6.5 x 3.5-4 microns. Found on the bark of maple and sycamore trees and on stored logs.
Cunninghamella Can cause disseminated and pulmonary infections in immune compromised hosts.
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Curvularia
Reported to be
allergenic and has been associated with
allergic fungal sinusitis. It may cause corneal
infections, mycetoma, and infections in immune
compromised hosts.
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Dictyosporium A fungal genus of the classification
group "Hyphomycetes". At this time, there is no
information available concerningDictyosporiumallergenicity or toxicity, but
as a member of the classification group "Dematiaceous
Hyphomycetes", it could potentially cause
phaeohyphomycosis (seephaeohyphomycosis). It is found in
terrestrial and freshwater habitats, and is a common
saprobe of submerged lignocellulose substances. The
microscope reveals its spores to be multicellular and
tongue-shaped; with subconcentric cells. Colonies may
appear dark brown, green-black, or black.
Dreschlera Conidia dimensions: 40-120 x 17-28
microns. Found on grasses, grains and decaying food.
It can occasionally cause a corneal infection of the
eye.
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Epicoccum
Conidia
dimensions: 15-25 microns. A common allergen.
It is found in plants, soil, grains, textiles
and paper products.
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Epidermophyton Can cause infections of skin (including
ringworm) and nails.
fungus Neither animals nor plants, these saprophytic and
parasitic spore-producing organisms rate a taxonomic
kingdom of their own. Fungi include molds, rusts,
mildews, smuts, mushrooms, puffballs, and yeasts. It
is estimated that more than 1.5 million species of
fungi exist.
Fusarium solani Aw 0.90. Macroconidia dimensions:
27-52 x 4.4-6.8; Microcondia dimensions: 8-16 x 2-4
microns. Found in plants and soils. Can produce
trichothecene toxins that may be associated with
disease in humans and
animals.
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Fusarium
Aw 0.90. A
common soil fungus. It is found on a wide range
of plants. It is often found in humidifiers.
Several species in this genus can produce
potent trichothecene toxins. The trichothecene
(scirpene) toxin targets the following systems:
circulatory, alimentary, skin, and nervous.
Produces vomitoxin on grains during unusually
damp growing conditions. Symptoms may occur
either through ingestion of contaminated grains
or possibly inhalation of spores. The genera
can produce hemorrhagic syndrome in humans
(alimentary toxic aleukia). This is
characterized by nausea, vomiting, diarrhea,
dermatitis, and extensive internal bleeding.
Reported to be allergenic. Frequently involved
in eye, skin, and nail infections.
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Geotrichum
Aw 0.90.
Conidia dimensions: 6-12 x 3-6 microns. Aw
0.90. A common contaminant of grains, fruits,
dairy products, paper, textiles, soil, and
water; often present as part of the normal
human flora. The speciesGeotrichum
candidumcan cause a secondary infection
(geotrichosis) in association with
tuberculosis. This rare disease can cause
lesions of the skin, bronchi, mouth, lung, and
intestine.
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Gliocladium A fungus that is structurally similar toPenicilliumsp. It is reported to be
allergenic.
Helicomyces A mitosporic mold often encountered
on decaying plant matter. The genus name prefix
"helico" is derived from the shape of the mold's
microscopic structure; certain filaments (sometimes
the conidia) curve into a helical path.
Reported effects upon human health
in the indoor environment are not available at
this time.
Scientists have shown the
interaction ofHelicomyces roseuswith
nitrogen-fixing bacteria to be a vital component
of an effective soil enriching system (where sugar
cane litter is the decomposition target).Helicomyces lilliputeushas long been
known as an important sewage treatment systems
decomposer, so it is not unexpected that other
members of this genus have been observed living on
wood submerged in water.
Helminthosporium Reported to be allergenic.
Histoplasma A fungus that has filamentous growth at 25
degrees C. and yeast growth at 37 degrees C. It is
reported to be a human pathogen. It may be associated
with birds.
Humicula Grows on products with a high cellulose
content. These fungi are also found in soil and on
plant debris.
hyaline
mycelia Mycelia that are
transparent, translucent, or colorless. If no
reproductive structures are present,
identification is difficult. Often associated with
allergic symptoms.
hypha (plural form: hyphae)
One of the tubular, filamentous, branching structures of a fungus (including
mold) that develop from germinated spores. A hypha is often divided into
sections (of several cells in linear succession) by cross walls called "septa" that
usually have perforations through which cytoplasm flows. It is the main means
of growth for fungi, and a collective or mass of hyphae is referred to as “mycelium”.
Memnoniella A
cellulolytic fungus that is very closely related toStachybotryssp. Both fungi have a worldwide
distribution and are often found together and are
commonly found in soil. Recent studies on mycotoxins
revealed thatMemnoniella echinatacan have a
toxicity similar to that of some isolates ofStachybotrys chartarum. Both produce varying
amounts of simple trichothecenes. Thus, it is
suggested thatMemnoniellasp. should also be
considered potentially dangerous in indoor air. The
major difference between the two fungi is that the
conidia ofMemnoniellasp. are in long
persistent chains while those ofStachybotrysare aggregated in slimy heads. Also the aerodynamic
diameter ofMemnoniellasp. conidia is smaller
and it would be expected to have an even greater
potential to penetrate deep into lungs than the
conidia ofStachybotryssp.
Microsporum Causes ringworm in humans.
mold Molds are a group of organisms that belong to the
taxonomic kingdom of Fungi. There are over 20,000
species of mold. Molds reproduce by making spores.
Mold spores waft through the indoor and outdoor air
continually. When mold spores land on a damp spot
indoors, they may begin growing and digesting
whatever they are growing on. Molds can grow on
virtually any organic substance, as long as moisture
and oxygen are present.
Monilia Reported to be allergenic. This fungus
produces soft rot of tree fruits. Other members
produce a red bread mold. It is infrequently involved
in corneal eye infections.
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Mucor
Often found in
soil, dead plant material, horse dung, fruits
and fruit juice. It is also found in leather,
meat, dairy products, animal hair, and jute. A
Zygomycetes fungus that may be allergenic (skin
and bronchial tests). This organism and other
Zygomycetes will grow rapidly on most fungal
media. May cause mucorosis in immune
compromised individuals. The sites of infection
are the lung, nasal sinus, brain, eye, and
skin. Infection may have multiple
sites.
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mycelium A mass of interwoven hyphae (a hypha is a filamentous
part of a fungus that usually has several cells in
linear succession with dividing walls in between)
that is often submerged in soil or organic matter or
the tissues of a host.
Myxomycetes A taxonomic
designation for fungi that are included in the
category of "slime molds". They're occasionally found
indoors, but mainly reside in forested regions on
decaying logs, stumps, and dead leaves. Myxomycetes
display characteristics of fungiandprotozoans. In favorable (wet) conditions they
exhibit motile, amoeba-like cells, usually bounded
only by a plasma membrane, that are variable in size
and form. During dry spells, they form a resting body
(sclerotium) with dry, airborne spores. These fungi
are not known to produce toxins, but can cause hay
fever and asthma.
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Nigrospora
Commonly found in warm
climates, this mold may be responsible for
allergic reactions such as hay fever and
asthma. It is found on decaying plant material
and in the soil. It is not often found
indoors.
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Oidium The asexual phase ofErysiphesp. It is a
plant pathogen causing powdery mildews. It is very
common on the leaves stems, and flowers of plants.
The health effects and allergenicity have not been
studied. It does not grow on non-living surfaces such
as wood or drywall.
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Paecilomyces
Commonly found
in soil and dust; less frequently in air.P.
variotiican cause paecilomycosis. Linked
to wood-trimmer's disease and humidifier
associated illnesses. They are reported to
allergenic. Some members of this genus are
reported to cause pneumonia. It may produce
arsine gas if growing on arsenic substrate.
This can occur on wallpapers covered with Paris
green.
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Papulospora These fungi are found in soil, textiles, decaying
plants, manure, and paper.
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Penicillium
Aw 0.78 - 0.88.
A wide number of organisms have been placed in
this genus. Identification to species is
difficult. Often found in aerosol samples.
Commonly found in soil, food, cellulose and
grains. It is also found in paint and compost
piles. It may cause hypersensitivity
pneumonitis or allergic alveolitis in
susceptible individuals. It is reported to be
allergenic (skin). It is commonly found in
carpet, wallpaper, and in interior fiberglass
duct insulation. Some species can produce
mycotoxins. Common cause of extrinsic asthma
(immediate-type hypersensitivity: type I).
Acute symptoms include edema and
bronchiospasms; chronic cases may develop
pulmonary emphysema. It may also cause
headaches, vomiting, and diarrhea.
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Periconia Found in soil, blackened and dead
herbaceous stems, leaf spots, grasses, rushes, and
sedges. Almost always associated with other fungi.
Rarely found growing indoors. Reportedly associated
with a rare case of mycotic keratitis.
p
erithecium
A fruiting
body of a fungus in which some types of spores
(including ascospores) are produced. (plural form:
perithecia)
Peronospora These species are plant pathogens and the
genus is one that causes downy mildews.Peronosporais very common and is an obligate
parasite (obligate parasites cannot grow on non
living environmental surfaces) found on leaves,
stems, flowers, and fruits of living higher plants.Peronosporasp. may be identified in air on
spore trap samples since spores have a distinctive
morphology. The spores may also be seen in dust as
part of the normal influx of outdoor microbial
particles. As of this writing, allergenicity has not
been studied and no information is available
regarding health effects or toxicity.
phaeohyphomycosis A hyphomycosis (infection by a mold of the taxonomic
designation "Hyphomycetes") in which the infiltrating
microbes are usually of the mold family
"Dematiaceae", and are characterized by the coloring
of their mycelium; the prefix "phaeo" means
"dusky-brown". Various forms of the disease involve
different areas of the body, such as the skin or
respiratory tract. Intrusion of the mold in the eye,
brain, bone, or subcutaneous tissue typically occurs
as a result of trauma to the affected area.
Phoma A common indoor air allergen that can
cause hay fever, asthma, and a type of
hypersensitivity pneumonitis commonly called "shower
curtain disease" (shower surfaces being among those
frequented by this fungal organism).Phomainfections in humans also have been reported; usually
affecting the immunocompromised, they include mycotic
keratitis (fungal infection of the cornea), skin
infections, and phaeohyphomycosis (seephaeohyphomycosis).
For a positive identification of
this genus, the specimen must contain the pycnidia (a
round to pear-shaped fruiting structure containing
conidia) to confirm the presence of simple phialides
(a cell from which conidia are extruded). A cultured
sample would provide these components. Colonies are
rapid growing, appear powdery to velvety, and exhibit
many different colors. This mold is known to grow on
butter, rice, potatoes, paint (sometimes seen as pink
and purple spots on painted walls), cement, rubber,
wood, paper, and under linoleum. In nature, the
species are found in soil, manure, on fruit, dead
plants, and as parasites on live plants.
Researchers have discovered that
whenPhoma macrostomais sprinkled onto the
soil in areas with no preexisting weeds, it acts as
an earth-friendly herbicide, inhibiting the ability
of many broadleaf plants (including dandelions) to
produce chlorophyll; the young broadleaf plants turn
white and die while grass seems to be unaffected.
Pithomyces A native of mostly tropical environments,
it commonly grows on dead plants, soil, wood, and
especially the dead leaves and grasses of livestock
fodder.Pithomyces chartarumproduces
sporidesmin (a piperazinedione), a mycotoxin known to
cause animal liver damage, and it causes facial
eczema in cattle, sheep, and goats. For humans, it is
considered a possible allergen, and a potential
infectious agent in immunocompromised patients.
Not known to be prolific indoors, this mold can
sometimes be found on paper. It exhibits distinctive
multi-celled brown conidia.
Rhizomucor The Zygomycetous fungus is reported to be
allergenic. It may cause mucorosis in immune
compromised individuals. It occupies a biological
niche similar toMucorsp. It is often linked
to occupational allergy. May cause mucorosis in
immune compromised individuals. The sites of
infection are the lung, nasal sinus, brain, eye, and
skin. Infection may have multiple sites.
Rhizopus The Zygomycetous fungus is reported to be
allergenic. It may cause mucorosis in immune
compromised individuals. It occupies a biological
niche similar toMucorsp. It is often linked
to occupational allergy. May cause mucorosis in
immune compromised individuals. The sites of
infection are the lung, nasal sinus, brain, eye, and
skin. Infection may have multiple sites.
Rhodotorula A reddish yeast typically found in moist
environments such as carpeting, cooling coils, and
drain pans. In some countries it is the most common
yeast genus identified in indoor air. This yeast has
been reported to be allergenic. Positive skin tests
have been reported. It has colonized terminally ill
patients.
rusts(and
smuts) These fungi are associated with plant diseases. In
the classification scheme of the fungi, the smuts
have much in common with the rusts, and they are
frequently discussed together. Both groups produce
wind-borne, resistant teliospores that serve as the
basis for their classification and their means of
spread. Rusts usually attack vegetative regions
(i.e., leaves and stems) of plants; smuts usually are
associated with the reproductive structures (seeds).
They can cause hay fever and asthma.
Saccharomyces Reported to be allergenic. Baker's
yeast.
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Scopulariopsis
It may produce
arsine gas if growing on arsenic substrate.
This can occur on wallpapers covered with Paris
green. It has been found growing on a wide
variety of materials, including house dust. It
is associated with type III
allergies.
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Sepedonium Most easily recognized by the spores,
which are colorless to yellow, spiny, round,
1-celled, and produced singly at the ends of short
filaments. Sometimes phialides of theAcremoniumorGabarnaudiatype may also
occur. A few species ofMortierella, as well
as the human pathogenHistoplasma capsulatum,
produce spores resembling those ofSepedonium.
Isolated from soil, but most commonly parasitized
mushrooms.
Serpula
lacrymans Common cause of extrinsic asthma
(immediate-type hypersensitivity: type I). Acute
symptoms include edema and bronchiospasms; chronic
cases may develop pulmonary emphysema.
smuts Seerusts.
Spegazzinia This mitosporic fungus (spores develop by means of
asexual cell division) is included in the
classification group "Hyphomycetes". At this time, no
information is available concerningSpegazziniaallergenicity or toxicity.Spegazziniaspores can be identified in air
samples by their distinctive structure, and have the
potential to produce a colony within seven to ten
days. Colonies are considered relatively slow
growing, and are brownish-black to black in color.
This saprobe (deriving its nourishment from nonliving
or decaying organic matter) is most commonly found in
warm-temperate to tropical areas in soil and on dead
leaves, stems, trees, and other various kinds of
plant debris.
spore The means by which molds reproduce. Spores are
microscopic (2-100 micrometers) and various shapes.
Distribution can be accomplished by a breeze, water
droplet, or a person or animal passing by. They can
even be discharged by the mold (usually under moist
conditions or high humidity).
Sporobolomyces Reported to be allergenic.
Sporoschisma A mitosporic fungal genus of the
classification group "Hyphomycetes". At this time, no
information is available concerningSporoschismaallergenicity or toxicity. It
is known to exist on wood and stems, and these can be
submerged in fresh water. Microscopic features
include quadriseptate spores, originating in an
enclosed membrane.
Sporothrix The speciesSporothrix schenckiican cause sporotrichosis, but usually only in
individuals that are immune compromised.
Sporotrichosis is a chronic fungal infection that
results when the mold enters the body where the skin
is damaged or via the lungs. If it reaches the
bloodstream, it can affect many other parts of the
body.
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Sporotrichum
Reported to be
allergenic. Additionally,Sporotrichum
pruinosumhas been observed in the
respiratory secretions of some human patients,
indicating a possible ability to colonize the
bronchopulmonary pathways.This genus does
not cause sporotrichosis (see alsoSporothrix, for there
is some taxonomic confusion between these two
genera).
Rarely found in
cooler regions,Sporotrichumis
prevalent in warm-temperate and tropical zones,
and grows (rapidly) on soils, decaying plant
matter, wet or rotting wood, grasses, and
landscaping mulch. Colonies may appear white,
rosy-beige, or orange, and have a velvety to
granular texture.
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Stachybotrys
Aw - 0.94 ,
optimum Aw ->0.98. Several strains of this
mold (S. atra, S. chartarum,andS.
alternansare synonymous) may produce
macrocyclic trichothecenes (one of which is
Satratoxin H) that are poisonous by inhalation.
These mycotoxins, when present, are primarily
associated with the mold's spores.
Individuals with chronic exposure toStachybotrys's toxins reported cold and
flu symptoms, sore throats, diarrhea,
headaches, fatigue, dermatitis, hair loss,
general malaise, and psychological depression.
For infants, the toxins create a vulnerability
to a serious condition called pulmonary
hemosiderosis (bleeding in the lungs) where
severe bleeding can result in coughing blood or
nosebleeds, and low grade bleeding can cause
chronic coughs and congestion with anemia.
People who unknowingly handled material
contaminated with this mold described symptoms
of cough, rhinitis, burning sensations of the
mouth and nasal passages, and cutaneous
irritation at the point of contact, especially
in areas of abundant perspiration. The toxins
produced by this mold will suppress the immune
system, affecting the lymphoid tissue and the
bone marrow. Animals injected with macrocyclic
trichothecenes exhibited the following
symptoms: necrosis and hemorrhage within the
brain, thymus, spleen, intestines, lung, heart,
lymph nodes, liver, and kidneys.
This is a dark-colored fungus that grows on
building materials with a high cellulose
content and a low nitrogen content. It is slow
growing when compared to other common molds,
and may not appear to compete well in their
presence. Yet, when moisture levels are high
for prolonged periods,Stachybotrysmay
gradually become the dominating genus (possibly
because of its yield of mycotoxins, which are
believed to be directed against other molds and
bacteria). This organism is usually difficult
to find in indoor air samples unless it is
physically disturbed, but when it does appear
it is an alert to find the source, as it will
likely be found growing in abundance. Its
spores--which can be found in a gelatinous
mass--will die readily after release, but are
still allergenic and can be toxigenic. Areas
with a relative humidity above 55%, and are
subject to temperature fluctuations, are ideal
for toxin production.
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S
temphylium
This genus is included in the taxonomic
designation "Hyphomycetes". It is a known allergen,
causing Type I allergies (examples: hay fever,
asthma). Phaeohyphomycotic sinusitis has been
reported in connection with this mold. (Seephaeohyphomycosis.)
Existing mainly in
the temperate northern hemisphere, it can be found in
soil, moist wood or cellulose materials, on
decomposing plants, and as pathogens on living plants
(leaf spots are one example). Colonies grow rapidly,
and appear velvety to cottony in texture; coloring is
light brown or olive green to black. Though it is
rare to find indoor colonization, it has been found
in dust that is transferred in from outside,
including dust on air filters.
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Syncephalastrum
Can cause a
respiratory infection characterized by a solid
intracaitary fungal ball.
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Taeniolella
(Phonetic Pronunciation: Tay-knee-ol’-el-luh) This genus of the
classification group "Dematiaceous Hyphomycetes" has been isolated
from human cutaneous and subcutaneous lesions, making it a possible etiological
agent of phaeohyphomycosis
(see phaeohyphomycosis). Studies of its allergenicity and toxicity are not
known at this time. Taeniolella lacks a known sexual state (placing it in the "Fungi
Imperfecti" category) and is known to reproduce asexually by the process
of mitosis. In temperate North America, this weak saprobe’s natural habitat
commonly includes dead branches, wood, and senescent leaves. Indoors, they
are sometimes found on lumber, other forms of wood, and plants. Taeniolella
may be identified from tape lift, bulk, or airborne spore samples.
Torula
Found outdoors in air, soil, on dead
vegetation, wood, and grasses. Also found indoors on
cellulosic materials. Reported to be allergenic and
may cause hay fever and asthma.
Trichocladium This is a widespread mitosporic (lacking a sexual
state) fungus of the classification group
"Hyphomycetes". There is little information regarding
toxicity or allergenicity, but it is known to rarely
be the causative agent for human keratitis (infection
of the cornea).
Various species of
this genus may be identified from indoor sampling
(one species in particular, Trichocladium
uniseptatum, is found regularly on indoor
environmental surfaces, especially wood). Outdoors,
it is found on dead wood, stems or twigs, tubers of
various plants, pine needles, other plant debris, and
in soils. It is notable that this microbe has been
associated with black root rot, as an aggressive
plant pathogen.
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Trichoderma
It is commonly
found in soil, dead trees, pine needles, paper,
and unglazed ceramics. It often will grow on
other fungi. It produces antibiotics that are
toxic to humans. It has been reported to be
allergenic. It readily degrades
cellulose.
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Trichophyton Can cause ringworm, athlete's foot, jock
itch, and other infections of the skin, nail, beard
and scalp. Reported to be allergenic. Found on soil
and skin.
Trichothecium Aw 0.90. Conidia dimensions: 12-23 x 8-10
microns. Found in decomposing vegetation, soil, corn
seeds, and in flour. The speciesTrichothecium
roseumcan produce a trichothecene toxin that may
be associated with disease in humans and other
animals. Reported to be allergenic.
Tritirachium Reported to be allergenic.
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Ulocladium
Aw 0.89. This mold is
reported to be a major allergen, capable of
causing hay fever and asthma. It is also known
to rarely cause subcutaneous infections. The
University of Adelaide, Australia, categorizes
this microbe in the classification group
"Dematiaceous Hyphomycetes", which includes it
as a possible causative agent of
phaeohyphomycosis (seephaeohyphomycosis).
Widely distributed in nature
and considered a saprobe (weak parasite), some
of its growth sites are soil, grasses, dead or
dying plants (mainly herbaceous vegetation),
manure, and compost. In interior environments
it has been found on paper, painted surfaces,
gypsum board, textiles, jute, straw materials,
carpets, cellulose building materials
(including wood), and in dust and air samples.
Colonies are moderately fast growing, usually
appearing olive-brown (or rusty-brown) to black
(or grayish), with a texture that is granular
to velvety.
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Verticillium Conidia dimensions: 2.3-10 x 1-2.6 microns.
Found in decaying vegetation, on straw, soil and
arthropods. A rare cause of corneal
infections.
Wallemia Aw 0.75. Conidia dimensions: 2.5-3.5
microns. Found in sugary foods, salted meats, dairy
products, textiles, soil, hay and fruits.
yeast Various yeasts are commonly identified on
air samples. Some yeasts are reported to be
allergenic. They may cause problems if a person has
had previous exposure and developed a
hypersensitivity. Yeasts may be allergenic to
susceptible individuals when present in sufficient
concentrations.
"Aw" refers to thewater activitymeasurement, where Aw is equal to the relative
humidity of the air surrounding the sample when
the air and the sample are at equilibrium (in an
enclosed space).
For help in finding word
definitions: http://ppathw3.cals.cornell.edu/glossary/Glossary.htm,"On-Line Glossary of Technical Terms in
Plant Pathology", provided by Cornell
University.
For additional information:
http://www.emlab.com/app/fungi/Fungi.po , "An Index of Some Commonly Encountered
Fungal Genera", provided by Environmental Microbiology Laboratory, Inc.
http://www.dehs.umn.edu/iaq_fib_fg_gloss.htm , "Fungal Glossary",
provided by the University of Minnesota Department of Environmental Health
and Safety.
http://www.emsl.com/index.cfm?nav=Pages&ID=149 , “Fungal Glossary” provided
by EMSL Analytical, Inc.
http://www.doctorfungus.org/thefungi/description_index.htm , "Fungi Descriptions",
provided by the DoctorFungus Corporation.
http://www.mercksource.com/pp/us/cns/cns_hl_dorlands_split.jsp?pg=/ppdocs/us/common/dorlands/dorland/misc/dmd-a-b-000.htm , "Dorland's Medical Dictionary", provided by W. B. Saunders.
http://en.wikipedia.org/ , “Wikipedia, The Free Encyclopedia” provided
by the Wikimedia Foundation, Inc.
http://www.merriam-webster.com/ , “Merriam-Webster's Medical Dictionary” provided
by Merriam-Webster, Incorporated.
http://dictionary.reference.com/ , “The American Heritage Science Dictionary” provided
by Dictionary.com, LLC.
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